the effect of omega-3 supplementation on serum levels of brain derived neurotrophic factor (bdnf) and oxidative stress following plyometric training in active men
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abstract
the aim of this study was to investigate the effect of omega-3 supplementation with 4 weeks of plyometric training on serum changes of brain derived neurotrophic factor (bdnf) and oxidative stress and their relationship in active men. 28 physical education male students (age 23.21±1.98 year, height 174.25±5.34 cm, weight 66.83±7.49 kg, bmi 20.03±2.25 kg/m2) were randomly divided into four groups including training + omega-3, omega-3, training, control. the training and training+omega-3 (combination) groups performed selected plyometric training for 4 weeks in 2 or 3 sets with 6 to 12 repetitions. also, supplementary (omega-3) and combination groups daily consumed 2 gr. omega-3 and 1 gr. starch (as a capsule) 3 times per day after their meals. training group received placebo capsules (starch with similar weight combined by saffron to provide color for an appearance and taste similar to omega-3 capsules). anova was used to examine inter-group differences and pearson correlation coefficient was applied to investigate the existence of any relationships among variables. a significant increase was observed in bdnf serum levels in combined and supplementation groups compared with the control group (p=0.001, p=0.004 respectively). serum levels of mda decreased significantly in supplementation group compared with control group (p=0.002). also, serum levels of sod in training group increased significantly compared with control group (p=0.042). likewise, only a correlation observed was observed between mda and sod in supplementation group (p=0.048, r=0.759). regular consumption of omega-3 supplementation combined with plyometric training increases bdnf and reduces mda. consequently, it can be used as a beneficial method to increase the health of the nervous system and to resist oxidative stress induced by exercise training.
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علوم زیستی ورزشیجلد ۸، شماره ۳، صفحات ۲۹۵-۳۰۹
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